[OA-28] The Milan system for reporting salivary gland cytopathology: a 7-year retrospective institutional study

Fine needle aspiration (FNA) cytology is efficient in guiding salivary gland lesions management. Lack of standardised reporting complicates communication between pathologists and clinicians. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has been proposed to improve reporting uniformity. This study aimed to reclassify salivary gland FNA and evaluate risk of malignancy (ROM) in each diagnostic category. All salivary gland FNA cytology in Srinagarind Hospital from January 2013 to December 2019...

[OA-27] A study of tumour-infiltrating lymphocyte in distal cholangiocarcinoma

Cholangiocarcinoma (CCA) is one of major cancer in Northeast Thailand. Studies reveal tumours can induce immune response due to their altered protein products recognised as foreign bodies by the immune system. Tumour-infiltrating lymphocytes (TILs) can be assessed to represent the mentioned immune response. Recently, TILs are a potential predictive factor of prognosis in many solid tumours; still, data researched in CCA are limited. This study aimed to assess TILs in distal cholangiocarcinoma according to The International TILs Working Group (ITWG) guideline and to correlate it with...

[OA-26] Prognostic significance of combined histologic factors, tumour budding and tumour-infiltrating lymphocyte, in patients with stage II colonic cancer

Colorectal cancer prognosis is based on conventional histologic factors, i.e. subtype, grade, size, lymphovascolar invasion, perineural invasion and margin status. The 5th edition of WHO classification of digestive tumours newly updates histologic factors, i.e. growth pattern, tumour budding (TB), poorly differentiated clusters (PDC), tumour-infiltrating lymphocyte (TIL) and Crohn-like reaction (CLR). This study aimed to assess conventional histologic factors and newly updated histologic factors. Haematoxylin and eosin stained slides of 41 patients with stage II ...

[OA-25] Diagnostic concordance of low-grade endometrial carcinoma between preoperative endometrial biopsy compared to hysterectomy specimen

The discordant histologic grade and subtype of endometrial carcinoma (EC) between the diagnosis of endometrial biopsy and hysterectomy specimen has an impact on patient management. This study aimed to compare the diagnosis of endometrial biopsy with hysterectomy specimen and to determine the histologic factors leading to the discordant grade and subtype. A retrospective study was conducted in 187 cases ...

[OA-24] The risk of non-standardised clinical chemistry assay in method verification

Before implementing Alinity c (Alinity) system, the verification procedure recommended by Clinical and Laboratory Standards Institute (CLSI) was followed on each assays. All parameters passed acceptable criteria of method verification except fructosamine assay. The objective of this study is to investigate the causes of unsuccessfol method verification. ...

[OA-23] Tropomyosin receptor kinase protein expression in Thai cholangiocarcinoma: clinicopathological correlation, pattern expression and prognosis

Tropomyosin receptor kinase (TRK) gene fusion has been found in associated with many tumours and coold be targeted treatment. Immunohistochemistry (IHC) expression of TRK is widely used to screening this alternation. The aim of this study was to investigate the expression of TRK protein detected by IHC in Thai cholangiocarcinoma (CCA) and to correlate with clinicopathological and survival data. Retrospective study of CCA patients who diagnosed from January 2011 to December 2015. ...

[OA-22] The adjusted protocol in cryosection of axillary sentinel lymph node reduces the overall diagnostic discordance

The cryosection of axillary sentinel lymph node is usefol for intraoperative decision in breast cancer patients. However, the consequence from cryosection-permanent section discordance, mainly from sampling error, still occurs. The aim of this study was to evaluate discordant rate, as well as its cause, of the adjusted protocol for cryosection in axillary sentinel lymph node compared to the traditional protocol. ...

[OA-20] High-risk histopathologic features of retinoblastoma: correlation with prognosis

Retinoblastoma is the most common malignant intraocolar tumour in children. It has been shown that adjuvant therapy following enucleation in patient with high-risk histopathologic features significantly decrease the mortality. We described the association of histopathologic features with prognostic factors. The aim of this study was to determine the correlation between histopathologic features and prognosis of retinoblastoma. ...

[OA-19] Comparing performance of two point-of-care testing (POCT) devices for haemoglobin measurement

Haemoglobin point-of-care test (POCT-Hb) devices can provide rapid evaluation for blood transfusion decisions in patients with critical bleeding at emergency, intensive care unit, and operating unit. The aim of this study was to compare the performance of two haemoglobin POC devices (HemoCue 201 DM and StatStrip Hb/Hct) in different specimen types. The first step, capillary, venous EDTA,...