Rate of Dyserythropoiesis-like Nuclear Changes in Erythroid Precursors in Bone Marrow

Dyserythropoiesis-like post-mortem changes in erythroid precursors at autopsy can look similar to certain kinds of pathologic processes. Objective: This study is to evaluate nuclear changes in erythroid precursors in marrow aspirate smears and histologic sections at different intervals...

Category : Special Articles

Is immunohistochemistry mandatory in staging bone marrow trephine biopsy of patients with diffuse large B-cell lymphoma (DLBCL)

Diffuse large B-cell lymphoma (DLBCL) can be found involving bone marrow in approximately 11-27% of cases 1. Patterns of involvement are variable; these include diffuse pattern (lymphomatous cells diffusely infiltrating the marrow), interstitial pattern (i.e. small amount of lymphomatous cells scattered among hematopoietic cells), nodular pattern (lymphomatous cells forming aggregates in intertrabecular or paratrabecular area of the marrow).. ...

Author : Jitsupa Treetipsatit, M.D.