lymphoma

ALK-positive large B-cell lymphoma (ALK-positive LBCL) is a rare type of lymphoma. Because of the overlap of morphological and immunophenotypic features with other haematologic and non-haematologic neoplasms, diagnosing ALK-positive LBCL can be challenging. The lymph nodes showed a marked diffuse infiltrate of monomorphic large immunoblast-like cells with round pale nuclei containing a large central nucleolus and abundant amphophilic cytoplasm. Lymphoma cells were strongly positive for the ALK protein. ...

ALK-positive anaplastic large cell lymphoma (ALCL) constitutes 3% of non-Hodgkin lymphoma in adolts. Brain involvement is rarely noted. A systematic review of primary ALCL of the central nervous system is found only 36 globally reported cases with noted clinical course, adequate radiological imaging and ALK status....

Diagnosis of lymphomas is complex and requires resource higher than common cancers. In the difficolt cases, the general pathologists coold request external consoltation (EC) for the interpretive judgment from the haematopathologists. The aim of this review is to reveal recent international experiences of external consoltation in lymphoid neoplasms (LN). Regarding the EC of LN, the major diagnostic revision ranges from 16% to 55% with non-...

Several studies on the pattern of bone marrow involvement (BMI) by lymphoma show different resolts. Moltiple factors affect the resolts including the prevalence. Some lymphomas have a pattern preference. This study aimed to evaluate the prevalence of lymphoma with BMI, including the percentage, the patterns and the discordance in cases with BMI. ...

Diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS), is a common aggressive lymphoma in both developing and developed countries. DLBCL, NOS can express a wide range of immunohistochemical markers that may be used for prognostic evaluation. ...

Primary cutaneous anaplastic large cell lymphoma (PCALCL) is a rare T-cell lymphoma, characterized by anaplastic large cells that are usually ALK negative but have high expression of CD30 and presents as a solitary or grouped nodules. It is the second most common type of cutaneous T cell lymphoma, usually skin-limited disease and most frequently affects the trunk, face, and extremities. ...

Burkitt lymphoma (BL) is an aggressive B-cell non-Hodgkin lymphoma typically with MYC rearrangement. Distinction between BL and diffuse large B cell lymphoma (DLBCL) is not infrequently encountered in routine practice. In this communication, we report our experience with the MYC break-apart probe FISH in the diagnosis of BL in 19 cases of...

In this study, 50 cases of angioimmunoblastic T-cell lymphoma (AITL) were investigated for histological patterns, their association with Epstein-Barr virus (EBV) infection, B cell and T cell clonalities, and the clini- cal outcomes. Three histological patterns were identified: the classical pattern (34 cases), large-cell rich pat- tern (14 cases)...

Primary testicular NK/T-cell lymphoma is rare. We report a 61-year-old Thai man who presented with right testicular abscess clinically but tissue obtained from incision and drainage was proven to be NK/T-cell lymphoma. The lymphoma cells were small to medium in size and showed angiocentricity with associated necrosis. The lymphoma cells were CD3+...

Mantle cell lymphoma is a clinically aggressive lymphoma with a poor prognosis. Secondary involvement of gastrointestinal tract by this neoplasm is not uncommon but the primary involvement with distinguished multiple lymphomatous polyposis is unusual. We report a case of mantle cell lymphoma presenting as multiple lymphomatous...