Comparison of α-SMA expression between squamous cell carcinoma and pseudoepitheliomatous hyperplasia

Juthamas Ngamwiseschaikul, Juthamas Wongphum, Somboon Keelawat

Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Background: The differentiation between invasive squamous cell carcinoma and reactive benign squamous proliferation has caused difficulties in general routine practice of pathology. Among several pathologic changes, desmoplastic reaction which represents myofibroblastic cell proliferation is one indicator for invasiveness of the cancer cells.