[P-34] Correlation between clinicopathology and the depth of chorionic villi invasion of placenta accreta spectrum

Yuktiana Kharisma1, 2, Hasrayati Agustina1, Birgitta M. Dewayani1, Sri Suryanti1 and Bethy S. Hernowo1

  1. Anatomical Pathology Department, Faculty of Medicine Universitas Padjadjaran / Dr Hasan Sadikin General Hospital, Bandung, Indonesia
  2. Anatomical Pathology Department, Faculty of Medicine Universitas Islam Bandung, Indonesia

 

Background and Objectives: The incidence of placenta accreta spectrum (PAS) has inclined with the increasing of cesarean deliveries (CD). It is divided into 3 groups based on the invasion of the chorionic villi into the myometrium (accreta, increta and percreta). The aim was to determine the correlation between clinicopathology and the depth of chorionic villi invasion of PAS.

Materials and Methods: This analytical descriptive study conducted from 66 cases from January 2015 to December 2020 at Dr Hasan Sadikin General Hospital Bandung. They were divided into 3 groups and had been evaluated based on maternal [age, gestational age (GA), parity, prior miscarriage and previous CD] and foetal [birth weight (BW) and APGAR score] characteristics. This study was analysed by a chi-square test.

Results: Placenta increta was the most cases (46.97%). The PAS mostly occurred at 30 – 34 years of age in all groups. A 32 – 37 weeks of GA, one to two parity (-ies) revealed accreta (52%, 74%) and increta (33%, 68%). Placenta percreta had 33% of 28 – 32-week GA and 56% was present in cases with ≥ 3 parities. Sixty-three % of accreta and 55% of increta did not have prior miscarriage; however, percreta group had it (78%). Almost all the group had at least one CD history. Normal foetal BW, APGAR score in accreta were 52%, 74%; increta were 48%, 74%; percreta were 56%, 89%, respectively. This study showed no statistically significant correlation of the maternal and foetal characteristics with PAS (p > 0.05).

Conclusion: There was no significant correlation between the clinicopathology and the depth of chorionic villi invasion of PAS.