The basic concepts of carcinogenesis
The aetiology of developing cancer consists of genetic and epigenetic mutations, DNA damage, genome instability, cancer stem cells, infectious agents, and carcinogens. However, carcinogenesis is a complex multistep process associated with various hereditary and environmental factors. ...
Cellular and somatic deaths
Cellular death generally results from irreversible (lethal) injury. In addition, a normal physiological cell death process or apoptosis presents during embryogenesis and adult life. The role of apoptosis is also involved in pathological condition. ...
Cellular injury
Cellular injury is the process through which the cell is unable to maintain its homeostasis in the encounter with injurious stimuli. Generally, the cells with mild injury result in reversible cell damage and there is no cellular death. However, severe cellular injury leads to irreversible change and death of the affected cells....
