Brief communications

Maternal floor infarction (MFI) and massive perivillous fibrin deposition (MPFD) are placental disorders of unknown aetiology, associated with adverse obstetric outcome. Its morphology is characterised by marked increase in perivillous fibrinoid deposition in the intervillous space. The distribution of such fibrinoid deposition in MFI and MPFD often overlaps, suggesting both conditions represented the final common pathway for a number of different insults....

Disseminated intravascular coagulation (DIC) is the excessive activation of the coagulation pathway with thrombus formation, progressing to a consumptive coagulopathy with an imbalance between the fibrinolytic and antifibrinolytic systems, resulting in uncontrolled haemorrhage. Sepsis is the most common condition associated with DIC, usually manifesting as diffuse bleeding, commonly involving the gastrointestinal tract. However, intraluminal intestinal haematoma leading to obstruction is rare, and such patients usually improve with management. We report what we believe is the first case of a fatal intraluminal intestinal hematoma in an infant with DIC....

The International Classification of Diseases for Perinatal Mortality (ICD-PM) coding was introduced in 2016, as a global system for reporting causes of perinatal death. The aim of this study was to classify stillbirths by the ICD-PM, comparing input from clinical data, placental pathology and autopsy results....

Tumours primarily arising from the appendix are not common, comprising only 0.9% - 1.4% of all documented appendectomies. Among all appendiceal neoplasms, majority of cases are of well-differentiated neuroendocrine tumours. Appendiceal leiomyosarcomas are rare with only a few cases reported. Thus, diagnosis and management of this tumour is based on the behaviour of leiomyosarcoma of the colon....

Malignant transformation (MT) arising from the mature cystic teratoma (MCT) is a rare occurrence, comprising about 1% – 3% in all documented MCTs. Majority of MT cases are squamous cell carcinoma, followed by adenocarcinoma, then neuroendocrine neoplasm. Bilateral ovarian MCT with both MTs of different types is extremely rare. This is the first documented case in the Philippines....

Primary central nervous system lymphoma (PCNSL) was an uncommon variant of extranodal non-Hodgkin lymphoma. Contrast-enhanced MRI imaging was the method of choice for detecting PCNSL. The purpose was to describe the MRI and pathologic features of PCNSL and to determine whether there was a correlation between it....

Diffuse large B-cell lymphoma (DLBCL) can be found involving bone marrow in approximately 11-27% of cases 1. Patterns of involvement are variable; these include diffuse pattern (lymphomatous cells diffusely infiltrating the marrow), interstitial pattern (i.e. small amount of lymphomatous cells scattered among hematopoietic cells), nodular pattern (lymphomatous cells forming aggregates in intertrabecular or paratrabecular area of the marrow).. ...