Brief communications

The use of whole slide imaging (WSI) for frozen section (FS) diagnosis is helpfol, particolarly in the setting of a shortage of pathologists. However, data on such an adoption is minimal in resource-limited settings. The aim of this study was to evaluate the accuracy of WSI for FS diagnosis of lymph node metastasis using a low-cost scanner. ...

Pathological reports play an important role in the treatment of cancer, and the College of American Pathologists (CAP) cancer protocol template is widely used. This study has the purpose to evaluate the completeness of the pathological report and factors that might contribute to it. ...

Diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS), is a common aggressive lymphoma in both developing and developed countries. DLBCL, NOS can express a wide range of immunohistochemical markers that may be used for prognostic evaluation. ...

A finding of islet cell hyperplasia has been reported in infants of diabetic mothers and hydrops foetalis (HF), but no any report in haemoglobin (Hb) Bart's HF. The aim of this study was to analyse the morphometry of beta cells in Hb Bart. Pancreas from 10 Hb Bart cases and 9 controls were retrieved. ...

National Blood Centre, Thai Red Cross Society screens blood samples from every donor for HIV with both serology and nucleic acid testing (NAT). Potential elite controllers (EC) are donors who tested reactive by serology, but non-reactive by NAT. ...

Intrauterine growth restriction (IUGR) is commonly found in women with severe pre-eclampsia. However, the placental pathologic findings are varied reported between cases with and without IUGR. The aim of this study was to compare the placental pathology between pregnant women complicated by severe pre-eclampsia with and without IUGR. ...

Gold standard of HER2 amplification detection is fluorescence in situ hybridisation (FISH), but it has several limitations. Many centres use dual-colour in situ hybridisation (DISH) assays to detect HER2 gene amplification, which is cost less and can be done in a general laboratory. ...

Type VII collagen is a main component of anchoring fibrils, providing stability to the dermal-epidermal adhesion. Its reduction or absence has been associated with an increased risk of squamous cell carcinoma (SCC). This study aimed to evaluate type VII collagen expression in oral SCC compared to normal oral mucosa and its relationship with cancer stages....

Prostate cancer is the second most common and the fifth leading cause of death by cancer in men worldwide. The most diagnosed type of prostate cancer is adenocarcinoma. ETS-like protein 1 (Elk-1) is a member of the ETS-domain transcription factor family. Elk-1 signaling pathways support growth and progression of tumour cells....

Known for their poor outcomes, triple-negative breast cancers (TNBCs) have been investigated for immune checkpoint inhibitors that target Programmed death ligand 1 (PD-L1). In the recent decade, tumour-infiltrating lymphocytes (TILs) have also become potential biomarkers. The aim of the study was to determine the reproducibility of PD-L1 scoring system and TILs interpretation in the local setting through intra- and interobserver agreement....