[OA-27] A study of tumour-infiltrating lymphocyte in distal cholangiocarcinoma

Cholangiocarcinoma (CCA) is one of major cancer in Northeast Thailand. Studies reveal tumours can induce immune response due to their altered protein products recognised as foreign bodies by the immune system. Tumour-infiltrating lymphocytes (TILs) can be assessed to represent the mentioned immune response. Recently, TILs are a potential predictive factor of prognosis in many solid tumours; still, data researched in CCA are limited. This study aimed to assess TILs in distal cholangiocarcinoma according to The International TILs Working Group (ITWG) guideline and to correlate it with...

[OA-23] Tropomyosin receptor kinase protein expression in Thai cholangiocarcinoma: clinicopathological correlation, pattern expression and prognosis

Tropomyosin receptor kinase (TRK) gene fusion has been found in associated with many tumours and coold be targeted treatment. Immunohistochemistry (IHC) expression of TRK is widely used to screening this alternation. The aim of this study was to investigate the expression of TRK protein detected by IHC in Thai cholangiocarcinoma (CCA) and to correlate with clinicopathological and survival data. Retrospective study of CCA patients who diagnosed from January 2011 to December 2015. ...

[OA-20] High-risk histopathologic features of retinoblastoma: correlation with prognosis

Retinoblastoma is the most common malignant intraocolar tumour in children. It has been shown that adjuvant therapy following enucleation in patient with high-risk histopathologic features significantly decrease the mortality. We described the association of histopathologic features with prognostic factors. The aim of this study was to determine the correlation between histopathologic features and prognosis of retinoblastoma. ...