Rate of Dyserythropoiesis-like Nuclear Changes in Erythroid Precursors in Bone Marrow
Dyserythropoiesis-like post-mortem changes in erythroid precursors at autopsy can look similar to certain kinds of pathologic processes. Objective: This study is to evaluate nuclear changes in erythroid precursors in marrow aspirate smears and histologic sections at different intervals...
Update in Thymoma for Surgical Pathologists
Thymoma is the most common mediastinal tumor in adulthood. By definition, it is a thymic epithelial neoplasm that displays at least some characteristics of normal thymus. Microscopically it comprises an admixture of thymic epithelial cells and immature T lymphocytes in various proportions and demonstrates marked intratumoral heterogeneity...
Acute and subchronic oral toxicity of xanthones extracted from the pericarp of Garcinia mangostana Linn.in rat
The purpose of this research was to study the acute and subchronic toxicity of crude mangosteen pericarp hydro extract, and determine the appropriate and safe amount of extract that may be consumed, through testing with Sprague Dawley rats of both sexes. The soft layer of the inner pericarp mangosteen fruits was immersed in water and boiled at 70 OC, and...
Contribution of MYC FISH in Pathological Diagnosis of Burkitt Lymphoma
Burkitt lymphoma (BL) is an aggressive B-cell non-Hodgkin lymphoma typically with MYC rearrangement. Distinction between BL and diffuse large B cell lymphoma (DLBCL) is not infrequently encountered in routine practice. In this communication, we report our experience with the MYC break-apart probe FISH in the diagnosis of BL in 19 cases of...
Myocardial infarction without coronary artery atherosclerosis: pathological aspect
Myocardial infarction (MI) is a clinico-pathological condition resulted from an irreversible ischemic injury to cardiac myocytes. Myocardial infarction with normal coronary artery on angiogram (MINCA) is a widelyaccepted clinical term used to describe a group of patients presenting with the MI symptoms and signs but having a normal angiogram....
Comparison of α-smooth muscle actin expression between squamous cell carcinoma and pseudoepitheliomatous hyperplasia
To evaluate the usefulness of α-smooth muscle actin (α-SMA) expression of reactive myofibroblastic cells within desmoplastic reaction tissue for distinction between invasive squamous cell carcinoma (SCC) and pseudoepitheliomatous hyperplasia (PEH)....
Standardization of the Colorectal Carcinoma Surgical Pathology Report
In 2010 Department of Pathology Siriraj Hospital had introduced a standardization program for reporting colorectal carcinoma. Then the completeness and accuracy of pathology reports were assessed. Slides were reviewed for accuracy of pT stage and rectal circumferential margin status. After standardization program the percentage of pT4 lesion...
Axillary lymph node ratio is an independent prognostic factor in Thai breast cancer patients
The number of metastatic lymph nodes to the total number of dissected axillary lymph nodes (lymph node ratio: LNR) is described as an independent prognostic factor in breast cancer patients, beside the traditional account of the number of axillary lymph node metastasis (pN stage). We investigated the correlation between LNR and prognosis among Thai...
Predictive Relevance of Tumor-infiltrating Lymphocytes in Breast Cancer
To determine the prognostic significance of the immunophenotype, density and distribution of tumor-infiltrating lymphocytes (TILs) in breast cancer samples....
Determination of Asbestos Bodies in Autopsy Lung Fluid
The finding of asbestos bodies in lung fluid aspirates represents definite evidence of having prior exposure to asbestos, and having asbestos fibers entering the bronchial tree. After entering the lung, fibers undergo a coating process with ferritin protein to form asbestos bodies. The present study was carried out with the aim of determining...
