Angioimmunoblastic T-Cell Lymphoma: an Epstein-Barr Virus-Associated, Bilineage Lymphoid Neoplasm

In this study, 50 cases of angioimmunoblastic T-cell lymphoma (AITL) were investigated for histological patterns, their association with Epstein-Barr virus (EBV) infection, B cell and T cell clonalities, and the clini- cal outcomes. Three histological patterns were identified: the classical pattern (34 cases), large-cell rich pat- tern (14 cases)...

Increases of pro-inflammatory cytokine expression in hippocampus following chronic paracetamol treatment in rats

Paracetamol is one of the most popular drugs used for treatment of pain and headaches. Recent evidences have indicated that long term treatment with this drug can induce the neurotoxic effect in the brain including in the hippocampal neurons, however the mechanism underlying its neurotoxic effect is still unclear. The present study aimed...

Comparison of Histopathology and Mammography for breast lesions. Retrospective study of 250 cases in Srinagarind Hospital, Khon Kaen, Thailand.

To assess the pathologic outcome of BI-RADS mammographic classification and the success of stereotactic biopsy for such lesions. Materials and...

Keyword : bi-rads, mammographic

Chondrosarcoma of distal phalanx with imaging study; a report of rare case with review of the literature

Chondrosarcoma of distal phalanx is extremely rare and to our best knowledge there was only one case having magnetic resonance ( MR ) imaging study. We report a case of 56-year-old woman developing chondrosarcoma of distal phalanx of the left ring finger. The radiographic and imaging studies highly suggested chondrosarcoma and amputation of distal...

Impact of CpG site specific methylation on silencing protein expression of GSTP1 in breast cancer

From previous study with Methylation specific polymerase chain reaction (MSP), there were cases of DNA methylation showing positive protein expression. Some CpG sites of the primer were speculated to have no effect on protein expression....

Is immunohistochemistry mandatory in staging bone marrow trephine biopsy of patients with diffuse large B-cell lymphoma (DLBCL)

Diffuse large B-cell lymphoma (DLBCL) can be found involving bone marrow in approximately 11-27% of cases 1. Patterns of involvement are variable; these include diffuse pattern (lymphomatous cells diffusely infiltrating the marrow), interstitial pattern (i.e. small amount of lymphomatous cells scattered among hematopoietic cells), nodular pattern (lymphomatous cells forming aggregates in intertrabecular or paratrabecular area of the marrow).. ...

Author : Jitsupa Treetipsatit, M.D.

Primary sinonasal mucosal melanoma with CD138 expressed plasmacytoid cells: a case report and review of literature

Primary sinonasal mucosal melanoma is a rare neoplasm. Like in other sites of malignant melanoma, the histopathology is variable and when lacking of melanin pigment, particularly in small biopsy specimen mimicks many neoplasms. Immunohistochemical staining plays an important role. Many immunomarkers, including S-100, HMB-45 and Melan-A should be...

Author : Narida Chirakalwasan, M.D.*

Increased eosinophil levels in HIV-infected patients with high CD4/CD8 ratio Study from 564 patients in Ramathibodi Hospital.

Blood from 564 patients infected with human immunodeficiency virus (HIV) were studied for laboratory analysis. The hematological changes including white blood cell count (WBC), percentage and absolute number of lymphocyte and eosinophil were determined by using the Technicon H*3 RTX hematological analyzer. Analysis of blood cell parameters...

Advantage of frozen section in management of thyroid nodule with preoperative fine needle aspiration in Siriraj Hospital, Bangkok, Thailand

We aimed to evaluate the role of frozen section (FS) and preoperative fine-needle aspiration cytology (FNA) in thyroid nodular lesions. ...

Sclerosing Polycystic Adenosis of the Parotid Gland: Report of A Case with Multifocality

Sclerosing polycystic adenosis (SPA) is a rare tumor-like lesion of the salivary gland that bears a histomorphological resemblance to fibrocystic disease and sclerosing adenosis of the breast. The lesion is widely considered to be a pseudoneoplastic inflammatory process. However, foci of epithelial dysplasia and carcinoma in situ can occur in the...