Sudden Death from Retroperitoneal Hemorrhage Due to Necrotizing Pancreatitis

We report a case of sudden death from retroperitoneal hemorrhage in 73-year-old male due to rupture of peri-pancreatic artery in acute necrotizing pancreatitis. This appears to be the first case report of sudden death from retroperitoneal hemorrhage due to pancreatitis. The rupture site was not identifiable by gross-exami- nation but it was confirmed...

Neuroendocrine Tumor of the Gallbladder with Hepatic Metastases: A Case Report

A 68-year-old woman presented with hepatic metastasis. She had been performed cholecystectomy at a provincial hospital for symptomatic gallstones and was diagnosed as poorly differentiated adenocarcinoma of the gallbladder. The follow-up hepatic segmentectomy revealed a malignant small round tumor composed of nests of cells containing small nuclei...

CD43 Expression in Malignant Melanoma: A Diagnostic Pitfall

CD43 is commonly concerned as a marker for hematopoietic cells and, at times, a preferential T-cell marker. However, a number of non-hematologic cancers, mostly carcinoma, can express CD43. Recently, a case of malignant melanoma mimicking malignant lymphoma by cytomorphology was reported to express CD43 as well as melanoma markers but the other hematologic...

Bursitis with pseudosarcomatous fibroblastic proliferation; a case report

Pseudosarcomatous fibroblastic proliferation (PSFP) is a quite common lesion found in various locations in- cluding soft tissue, bone and other organs and often raises a difficult differential diagnosis with malignancy. However, PSFP has not been described in tissue related to bursitis. We report a case of 31-year-old male who developed a cystic...

Incomplete pentalogy of Cantrell: a case report

Pentalogy of Cantrell is a rare congenital syndrome characterized by defects involving the supra-umbilical abdominal wall, lower sternum, anterior diaphragm, pericardium, and the intra-cardiac anomalies. The ensuing congenital heart disease is a source of major morbidity. The full spectrum of the syndrome is rare while incomplete expression of the...

Primary central nervous system lymphoma presenting with panhypopituitarism and diabetes insipidus

Lymphoma involving the hypothalamus is very rare. We present a case of a 48-year-old man with primary central nervous system lymphoma (PCNSL) presenting with hypothalamic and pituitary stalk lesions with frontal masses, causing diabetes insipidus and panhypopituitarism. Brain MRI with gadolinium enhancement demonstrated vivid enhancing hypothalamic and...

Disseminated Tuberculosis in a Mother with Diffuse Large B-cell Lymphoma resulting in Placental and Inferred Congenital Tuberculosis: An Autopsy Case Report

Tuberculosis of the placenta is a rare condition which mainly occurs in the immunosuppressed individuals especially in acquired immune deficiency syndrome (AIDS) and hematologic malignancy9. Tuberculosis can spread to the fetus via hematogenous or cervicovaginal route and result in congenital tuberculosis....

Update in Thymoma for Surgical Pathologists

Thymoma is the most common mediastinal tumor in adulthood. By defi nition, it is a thymic epithelial neoplasm that displays at least some characteristics of normal thymus. Microscopically it comprises an admixture of thymic epithelial cells and immature T lymphocytes in various proportions and demonstrates marked intratumoral...

Transformation in Malignant Lymphoma: Morphologic Approach

Morphologic approach is still very crucial to detect transformation in malignant lymphoma. With the knowledge of each malignant lymphoma type, especially the clinical course, a number of lymphoma can have histologic progression as evidence of transformation as follow: large cell transformation, blastic transformation, and histiocytic...

The Many Faces (and Origins) of Adenocarcinoma in the Liver: Pattern Approach to Diagnosis on Small Tissue Samples

Focal liver lesions can be solitary or multiple, solid or cystic, congenital or acquired, and range from cysts, hamartomas, hyperplastic nodules and inflammatory entities to tumors and tumor-like lesions. The background liver may be normal or diseased. An algorithmic approach based on pattern recognition and cell profiling is outlined for the ...