Rhinosporidiosis of maxillary sinus: an unusual site – a case report

Rhinosporidiosis is a rare and chronic infestation caused by fungus Rhinosporidium seeberi, seen in India and Sri Lanka and is hyperendemic in southern parts of Tamil Nadu. It predominantly affects mucus membrane of nose and nasopharynx causing polypoidal growth....

Protective effect of angiopoietin 2 on cardiomyocytes against simulated ischemic injury

Angiopoietin 1 (Angpt1) and Angiopoietin 2 (Angpt2) are vascular growth factors that play important roles in vascular angiogenesis and adult vasculature maintenance. Previous studies reported that Angpt1 reduced the size of myocardial infarction in in vivo myocardial infarction experiment in rats, while Angpt2  protein levels increased in myocardial infarction areas. ...

Cytotoxic effect of lutein extracts from marigold flower in Lens epithelial cell line

Lutein is a carotenoid found in the lens of the human eyes. Its functions are to protect the eyes by filtering a hazard blue light and to prevent vision loss due to cataract formation. Lutein could not be synthesised in the body and must be taken from the diet, however, lutein is isolated from a marigold flower....

A Comparison Study of Molecular Classification of Primary Invasive Breast Carcinoma and Corresponding Metastatic Carcinoma in Axillary Lymph Nodes by Immunohistochemistry

Breast cancer is a heterogeneous disease. There is a high degree of diversity between and within tumours as well as among cancer-bearing individuals, and all of these factors together determine the risk of disease progression and therapeutic resistance....

Pathological Assessment of Activity and Chronicity Indices in Lupus Nephritis Patients

Lupus nephritis (LN) is one of a major complication of systemic lupus erythematosus (SLE). Ten percent of patients with LN will develop end-stage renal disease (ESRD). Renal biopsy is the gold standard for diagnosis of LN and evaluate activity and chronicity of disease to predict renal function outcome....

Effect of healthy lifestyle on lipid profile in a young women with overweight

In the past decades, the prevalence of overweight and obesity have increased substantially worldwide, especially in South-East Asia countries including Thailand. Recent data from prospective studies have indicated that overweight and obesity in children and adolescents are predictors of adult obesity....

Physicians’ knowledge, attitude and practices towards autopsy in a Nigerian tertiary hospital

The post-mortem examination is a hospital service necessary to diagnose the cause and circumstances surrounding patients' death. This study assessed the knowledge, attitude and practices of physicians towards autopsy. Descriptive cross-sectional study of physicians that completed a semi-structured questionnaire assessing their knowledge...

Increased cardiac troponin T concentrations in a young obese man with chest pain and non-obstructive coronary arteries

Acute myocardial infarction in young patients with non-obstructive coronary arteries is rare and has been rarely reported in the literature. We report herein a case of an obese young man presented to the emergency department with typical chest pain, ischaemic ECG changes, and elevated cardiac troponin T concentrations...

The detection of HLA-B27 allele types by quantitative real-time polymerase chain reaction with melting curve analysis

Human leucocyte antigen B27 (HLA-B27) is a major histocompatibility complex class 1 molecule that is strongly associated with ankylosing spondylitis. The polymerase chain reaction with sequence specific primers (PCR-SSP) is currently used for the discrimination of HLA-B27 allele types resulting from single base substitutions....

The essentials of vascular pathology

Vascular pathology is defined as the abnormalities of the arterial and venous blood vessels and the lymphatic vessels. Endothelial cell injury usually leads to the development of either arterial or venous change.The lymphatic diseases mostly result from inflammation, infection, and neoplasm....